Expert: Humanized monoclonal antibody that binds sclerostin, inhibiting its negative regulation of the Wnt signaling pathway, thereby increasing bone formation and decreasing bone resorption.
Everyday: Blocks sclerostin, a protein that stops bone formation, allowing bones to grow stronger.
+34% YoY to $2.1B. Strong growth driven by increasing osteoporosis awareness and bone-building differentiation vs anti-resorptives. Co-developed with UCB.