Hypertension

HTN · CVRM · 2 drugs · 3 indications

Elevated blood pressure. Includes treatment-resistant hypertension.
Competitive Landscape (2 drugs)
DrugCompanyMechanismModalityRouteStage
baxdrostatAZNAldosterone synthase inhibitorSmall moleculeORALFILED
ZilebesiranAZN, ALNYAngiotensinogen silencingsiRNASCPHASE3
Indications (3)
Hypertension
Zilebesiran PHASE3
Uncontrolled hypertension
baxdrostat PHASE3
Treatment-resistant hypertension
baxdrostat PHASE3
Upcoming Catalysts
Baxdrostat - Hypertension - FDA ApprovalREGULATORY
AZNQ2 2026
Zilebesiran - Hypertension - Ph3 - ToplineCLINICAL
ROG.SW2027
Data from Supabase · Updated 2026-03-24