baxdrostat baxdrostat FILED
Drug Profile
ModalitySmall molecule
RouteORAL
Therapy AreaCVRM
Peak Sales Est$2500M
Formulations[]
Companies
AZN (ORIGINATOR)100%
Mechanism: Aldosterone synthase inhibitor
Expert: Selective inhibitor of CYP11B2 (aldosterone synthase) that reduces aldosterone production while sparing cortisol synthesis.
Everyday: Blocks production of a hormone that raises blood pressure, for patients whose blood pressure is hard to control.
Targets: ["CYP11B2"]
Programs (2)
IndicationStageKey StudyRegional Status
TR-HTNPHASE3HALO[]
UC-HTNPHASE3HALO[]
Upcoming Catalysts (1)
Baxdrostat - Hypertension - FDA Approval Q2 2026
Notes
Aldosterone synthase inhibitor. First-in-class. PDUFA Q2'26.
Data from Supabase · Updated 2026-03-24