Remibrutinib LOU064 FILED
Drug Profile
ModalitySmall molecule
RouteOral
Therapy AreaImmunology
Peak Sales Est$2500M
Formulations[]
Companies
NVS (ORIGINATOR)100%
Mechanism: BTK inhibitor
Expert: Selective covalent inhibitor of Bruton's tyrosine kinase that disrupts B-cell receptor signaling critical for CLL and MCL survival.
Everyday: Blocks a protein that B-cell cancers need to survive and grow.
Targets: ["BTK"]
Programs (1)
IndicationStageKey StudyRegional Status
CIndUFILEDREMIX-1/2[]
Upcoming Catalysts (2)
Remibrutinib - Hidradenitis Suppurativa - Ph3 - Topline H2 2026
Remibrutinib - CIndU - Ph3 - Topline H2 2026
Notes
Highly selective covalent BTK inhibitor for chronic spontaneous urticaria. Designed to minimize off-target kinase inhibition; targets B-cell and mast cell signaling in refractory urticaria.
Data from Supabase · Updated 2026-03-24