Drug Profile
ModalityMonoclonal antibody
RouteSC
Therapy AreaOncology
Launch2010-11-18
Peak Sales Est$2300M
Formulations[{"id":"xgeva-sc","doses":"120mg/1.7mL","route":"SC","setting":"HCP_ADMINISTERED","frequency":"Q4W",
Expert: Fully human IgG2 monoclonal antibody targeting RANK ligand (RANKL). Inhibits osteoclast formation, function, and survival, reducing bone resorption.
Everyday: Blocks a signal (RANKL) that tells bone-eating cells to break down bone. Without this signal, your bones stay stronger and denser — like telling the demolition crew to stop working.
Targets: ["RANKL"]