Expert: Fully human monoclonal antibody cocktails targeting major allergen proteins. REGN1908-1909: targets Fel d 1 (major cat allergen). REGN5713-5715: targets Bet v 1 (major birch pollen allergen). Neutralizes allergens before IgE cross-linking on mast cells.
Everyday: Antibodies designed to neutralize specific allergens (like cat dander protein Fel d 1 or birch pollen protein Bet v 1) before they can trigger allergic reactions. Rather than suppressing the entire immune system, these drugs simply mop up the specific substance causing the allergy.
Targets: ["Fel d 1","Bet v 1"]
Three-antibody cocktail targeting Bet v 1 (major birch tree pollen allergen). Same approach as cat allergy program. If both allergy programs succeed, REGN could create an entirely new allergen-neutralization therapeutic class.