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Truqap
capivasertib
APPROVED
Drug Profile
Modality
Small molecule
Route
ORAL
Therapy Area
Oncology
Launch
2023-11-16
US LOE
2036-01-01
Peak Sales Est
$2000M
Formulations
[{"id":"truqap-oral","doses":"160mg tablets","route":"Oral","setting":"PATIENT_SELF","frequency":"Tw
Companies
AZN
(ORIGINATOR)
100%
Mechanism: AKT inhibitor
Expert:
Selective ATP-competitive pan-AKT kinase inhibitor that blocks PI3K/AKT pathway signaling in tumors with PIK3CA/AKT1/PTEN alterations.
Everyday:
Blocks a protein that helps cancer cells grow and resist treatment.
Targets: ["AKT"]
Revenue History
Period
Revenue ($M)
2024
$185M
Q1 2025
$75M
Q2 2025
$95M
Programs (1)
Indication
Stage
Key Study
Regional Status
HR+/HER2- BC
APPROVED
CAPItello-291
[{"stage":"APPROVED","region":"US","approval_date":"2023-11-16"},{"stage":"APPRO
Notes
AKT inhibitor for breast cancer.
Data from Supabase · Updated 2026-03-24