REGN1908-1909 REGN1908-1909 PHASE3
Drug Profile
ModalityMonoclonal antibody cocktail
RouteSC
Therapy AreaImmunology
Peak Sales Est$1000M
Formulations[]
Companies
REGN (ORIGINATOR)100%
Mechanism: Allergen-specific monoclonal antibody
Expert: Fully human monoclonal antibody cocktails targeting major allergen proteins. REGN1908-1909: targets Fel d 1 (major cat allergen). REGN5713-5715: targets Bet v 1 (major birch pollen allergen). Neutralizes allergens before IgE cross-linking on mast cells.
Everyday: Antibodies designed to neutralize specific allergens (like cat dander protein Fel d 1 or birch pollen protein Bet v 1) before they can trigger allergic reactions. Rather than suppressing the entire immune system, these drugs simply mop up the specific substance causing the allergy.
Targets: ["Fel d 1","Bet v 1"]
Programs (1)
IndicationStageKey StudyRegional Status
Cat allergyPHASE3Cat allergy Ph3[]
Notes
Two-antibody cocktail targeting Fel d 1 (major cat allergen protein). Novel approach: neutralizes the allergen itself rather than suppressing the immune system. Massive addressable market (~10% of population is cat allergic). Ph3 ongoing.
Data from Supabase · Updated 2026-03-24