Expert: Inhibitor of decaprenylphosphoryl-β-D-ribose 2-epimerase (DprE1), an essential enzyme in mycobacterial arabinogalactan biosynthesis. Disrupts cell wall integrity of Mycobacterium tuberculosis, including MDR and XDR strains.
Everyday: Blocks an enzyme that TB bacteria need to build their protective cell wall. Without this wall, the bacteria become vulnerable and die — even drug-resistant strains that have learned to dodge other antibiotics.
Targets: []