Chronic myelomonocytic leukemia

CMML · Hematology · 1 drugs · 1 indications

A blood cancer that sits between myelodysplastic syndromes (MDS) and myeloproliferative neoplasms (MPN). Bone marrow makes too many monocytes (a type of white blood cell). Median age at diagnosis ~70. Limited treatment options. Can transform to acute leukemia.

Competitive Landscape (1 drugs)

Drug	Company	Mechanism	Modality	Route	Stage
Vonjo	SOBI	JAK2/IRAK1 inhibitor	Small molecule	PO	APPROVED

Indications (1)

CMML

Vonjo PHASE2

Upcoming Catalysts

Vonjo - MF (severe thrombocytopenia) - Ph3 - Confirmatory (PACIFICA)CLINICAL

SOBI2026-2027

Data from Supabase · Updated 2026-03-24