Pseudobulbar Affect

PBA · Neurology · 1 drugs · 1 indications

Neurological condition causing involuntary, sudden episodes of crying or laughing disproportionate to emotional state. Occurs secondary to ALS, MS, stroke, or TBI.

Competitive Landscape (1 drugs)

Drug	Company	Mechanism	Modality	Route	Stage
Nuedexta	4578	NMDA Antagonist / Sigma-1 Agonist	Small molecule	ORAL	APPROVED

Indications (1)

Pseudobulbar Affect (PBA)

Nuedexta APPROVED

Data from Supabase · Updated 2026-03-24